Spatial mapping of mitochondrial networks and bioenergetics in lung cancer.

doi:10.1038/s41586-023-05793-3

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Article

Spatial mapping of mitochondrial networks and bioenergetics in lung cancer.

Nature - 1 Mar 2023

Han Mingqi, Bushong Eric A, Segawa Mayuko, Tiard Alexandre, Wong Alex, Brady Morgan R, Momcilovic Milica, Wolf Dane M, Zhang Ralph, Petcherski Anton, Madany Matthew, Xu Shili, Lee Jason T, Poyurovsky Masha V, Olszewski Kellen, Holloway Travis, Gomez Adrian, John Maie St, Dubinett Steven M, Koehler Carla M, Shirihai Orian S, Stiles Linsey, Lisberg Aaron, Soatto Stefano, Sadeghi Saman, Ellisman Mark H, Shackelford David B

Abstract excerpt

Mitochondria are critical to the governance of metabolism and bioenergetics in cancer cells1. The mitochondria form highly organized networks, in which their outer and inner membrane structures define their bioenergetic capacity2,3. However, in vivo studies delineating the relationship between the structural organization of mitochondrial networks and their bioenergetic activity have been limited. Here we present...

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PMID: 36922590
DOI: 10.1038/s41586-023-05793-3
PMCID: PMC10033418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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