Article

HER2-driven mammary tumorigenesis enhances bioenergetics despite reductions in mitochondrial content

2024-11-03

Abstract excerpt

<h4>ABSTRACT</h4> It is now recognized that mitochondria play a crucial role in tumorigenesis, however, it has become clear that tumor metabolism varies significantly between cancer types. The failure of recent clinical trials aimed at directly targeting tumor respiration through oxidative phosphorylation inhibitors underscores the critical need for further studies providing an in-depth evaluation of mitochondria...

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Literature Corpus work: 1a6b58de-2f68-5d92-a615-3f1523926c12
DOI: 10.1101/2024.11.03.621754

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