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Article

The role of mitochondrial electron transport in tumorigenesis and metastasis.

Biochimica et biophysica acta - 1 Apr 2014

Tan An S, Baty James W, Berridge Michael V

Abstract excerpt

BACKGROUND: Tumor formation and spread via the circulatory and lymphatic drainage systems is associated with metabolic reprogramming that often includes increased glycolytic metabolism relative to mitochondrial energy production. However, cells within a tumor are not identical due to genetic change, clonal evolution and layers of epigenetic reprogramming. In addition, cell hierarchy impinges on metabolic status...

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PMID: 24141138
DOI: 10.1016/j.bbagen.2013.10.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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