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A novel computational tool for tracking cancer energy hijacking from immune cells

1 Jan 2024

Abstract excerpt

Recent studies revealed a new biological process that malignant cancer cells hijack mitochondria from nearby T cells, providing another potential mechanism for immune evasion. We further confirmed this process at the single-cell genomic level through MERCI, a novel algorithm for tracking mitochondrial (MT) transfer. Applied to human cancer samples, MERCI identified a new cancer phenotype linked to MT hijacking,...

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PMID: 38193607
DOI: 10.1002/ctm2.1533

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