Article

Assessing Runs of Homozygosity: A comparison of SNP Array and Whole Genome Sequence low coverage data

2017-07-07

Abstract excerpt

Runs of Homozygosity (ROH) are sequences that arise when identical haplotypes are inherited from each parent. Since their first detection due to technological advances in the late 1990s, ROHs have been shedding light on human population history and deciphering the genetic basis of monogenic and complex traits and diseases. ROH studies have predominantly exploited SNP array data, but are gradually moving to whole g...

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Literature Corpus work: dd2ba52c-f341-5410-8b37-c198b18557ad
DOI: 10.1101/160705

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