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Assessing runs of Homozygosity: a comparison of SNP Array and whole genome sequence low coverage data.

BMC genomics - 30 Jan 2018

Ceballos Francisco C, Hazelhurst Scott, Ramsay Michèle

Abstract excerpt

BACKGROUND: Runs of Homozygosity (ROH) are genomic regions where identical haplotypes are inherited from each parent. Since their first detection due to technological advances in the late 1990s, ROHs have been shedding light on human population history and deciphering the genetic basis of monogenic and complex traits and diseases. ROH studies have predominantly exploited SNP array data, but are gradually moving...

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PMID: 29378520
DOI: 10.1186/s12864-018-4489-0
PMCID: PMC5789638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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