How to study runs of homozygosity using PLINK? A guide for analyzing medium density SNP data in livestock and pet species.

Abstract excerpt

BACKGROUND: PLINK is probably the most used program for analyzing SNP genotypes and runs of homozygosity (ROH), both in human and in animal populations. The last decade, ROH analyses have become the state-of-the-art method for inbreeding assessment. In PLINK, the --homozyg function is used to perform ROH analyses and relies on several input settings. These settings can have a large impact on the outcome and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gene Frequency
• Share to Genetic Testing
• Share to Genetics, Population