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Article

Detecting regions of homozygosity to map the cause of recessively inherited disease.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Kijas James W

Abstract excerpt

Homozygosity is a component of genetic patterning that can be used to search for the cause of genetic disease. In this chapter, methods are presented to analyze SNP data for the presence of homozygosity. Two exercises demonstrate methods to define runs of homozygosity, to identify shared homozygosity between individuals, and to evaluate the results in light of the expectations of a recessively inherited genetic...

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PMID: 23756898
DOI: 10.1007/978-1-62703-447-0_14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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