Article
Crucial motifs and residues in the extracellular loops influence the formation and specificity of connexin docking.
Biochimica et biophysica acta. Biomembranes - 1 Jan 2018
Bai Donglin, Yue Benny, Aoyama Hiroshi
Abstract excerpt
Most of the early studies on gap junction (GJ) channel function and docking compatibility were on rodent connexins, while recent research on GJ channels gradually shifted from rodent to human connexins largely due to the fact that mutations in many human connexin genes are found to associate with inherited human diseases. The studies on human connexins have revealed some key differences from those found in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
