Article

Type I Interferon Regulation of HLA-F Expression in Human Trophoblasts During Viral Infection

2026-05-12

Abstract excerpt

The role of human leukocyte antigen F (HLA-F) at the maternal-fetal interface (MFI) during viral infection and its regulation by interferon signaling remains poorly understood. Here, we investigated HLA-F expression and regulation in first-trimester trophoblast cells following activation of the type I interferon pathway and viral infection. We demonstrate that HLA-F is significantly upregulated at both mRNA and pr...

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Literature Corpus work: dccfd8e6-3f6f-5fa7-b412-363319d4c7ac
DOI: 10.20944/preprints202605.0746.v1

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