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Primary Trophoblast Cultures: Characterization of HLA Profiles and Immune Cell Interactions

13 May 2022

Abstract excerpt

Introduction: Trophoblasts are essential in fetal-maternal interaction during pregnancy. The goal was to study HLA profiles of primary trophoblasts derived from placentas, and to investigate their usefulness in studying interaction with immune cells. Methods: After enzymatic digestion of first-trimester placental tissue from seven donors (6-9 weeks gestation) and trophoblast enrichment we cultured...

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PMID: 35634345
DOI: 10.3389/fimmu.2022.814019

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