Article

DUX4-stimulated genes define an antiviral defense program in human placental trophoblasts

2025-01-24

Abstract excerpt

The placenta combats mother-to-fetus transmission of viruses through the antiviral activities of fetal-derived trophoblasts. Placental trophoblasts employ specialized antiviral strategies to protect against infection while preventing maternal immune rejection of the fetus. However, the full extent of how trophoblasts respond to viral infections is not well understood. To address this, we defined the transcriptiona...

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Identifiers and source

Literature Corpus work: 98927f3c-cc33-578b-958c-4e738aea60a3
DOI: 10.1101/2025.01.22.634317

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