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Article

Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twins.

PLoS neglected tropical diseases - 1 Aug 2020

Amaral Murilo Sena, Goulart Ernesto, Caires-Júnior Luiz Carlos, Morales-Vicente David Abraham, Soares-Schanoski Alessandra, Gomes Roselane Paiva, Olberg Giovanna Gonçalves de Oliveira, Astray Renato Mancini, Kalil Jorge E, Zatz Mayana, Verjovski-Almeida Sergio

Abstract excerpt

Zika virus (ZIKV) causes congenital Zika syndrome (CZS), which is characterized by fetal demise, microcephaly and other abnormalities. ZIKV in the pregnant woman circulation must cross the placental barrier that includes fetal endothelial cells and trophoblasts, in order to reach the fetus. CZS occurs in ~1-40% of cases of pregnant women infected by ZIKV, suggesting that mothers' infection by ZIKV during...

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Identifiers

PMID: 32745093
DOI: 10.1371/journal.pntd.0008424
PMCID: PMC7425990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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