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Article

Protective and Pathogenic Effects of Interferon Signaling During Pregnancy

23 Sept 2019

Abstract excerpt

Immune regulation at the maternal-fetal interface is complex due to conflicting immunological objectives: protection of the fetus from maternal pathogens and prevention of immune-mediated rejection of the semiallogeneic fetus and placenta. Interferon (IFN) signaling plays an important role in restricting congenital infections as well as in the physiology of healthy pregnancies. In this review, we discuss the...

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PMID: 31545139
DOI: 10.1089/vim.2019.0076

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