Article

Single-cell gene regulatory network analysis reveals new melanoma cell states and transition trajectories during phenotype switching

2019-07-26

Abstract excerpt

Melanoma is notorious for its cellular heterogeneity, which is at least partly due to its ability to transition between alternate cell states. Similarly to EMT, melanoma cells with a melanocytic phenotype can switch to a mesenchymal-like phenotype. However, scattered emerging evidence indicates that additional, intermediate state(s) may exist. In order to search for such new melanoma states and decipher their unde...

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Literature Corpus work: dc8be34c-3e5e-5453-9bf3-768a22f5936e
DOI: 10.1101/715995

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