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Single-cell analysis unveils cell subtypes of acral melanoma cells at the early and late differentiation stages

30 Dec 2024

Abstract excerpt

BACKGROUND: Melanoma, a malignant neoplasm originating from melanocytes, is a form of skin cancer with rapidly increasing global incidence, often exacerbated by UV radiation[1]. Particularly, acral melanoma, characterized by its swift metastasis and poor prognosis, underscores the significance of further research into its heterogeneity. Single-cell sequencing has been widely utilized in the study of tumor...

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PMID: 39781353
DOI: 10.7150/jca.102045

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