Article

Ablation of <i>Max</i> expression induces meiotic onset in sexually undifferentiated germ cells

2023-06-11

Abstract excerpt

Meiosis is a specialized type of cell division that occurs only in germ cells physiologically. We have previously demonstrated that MYC-associated factor X (MAX) is involved in blocking ectopic and precocious meiotic onsets in embryonic and germline stem cells, respectively, as a central component of the PRC1 subtype PRC1.6. In this study, we investigated the role of the Max gene in germ cells in vivo . Our data...

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Literature Corpus work: 9183694a-44be-5a77-9681-0c36f5b3984c
DOI: 10.1101/2023.06.10.544477

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