Article

Early Endosome Capture Proteomics and its Application to Amyloid Precursor Protein Intramembrane Processing by β and γ-Secretases

2022-03-31

Abstract excerpt

<h4>SUMMARY</h4> Degradation and recycling of plasma membrane-localized proteins occurs via the endolysosomal system, wherein endosomes bud into the cytosol from the plasma membrane and subsequently mature into degradative lysosomal compartments. The endolysosomal system also participates in intracellular membrane protein trafficking, signaling, and protein degradation via autophagy. Our understanding of the endo...

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Literature Corpus work: 8c4416c0-e2d2-5e19-b37a-c5fa6f8481cb
DOI: 10.1101/2022.03.31.486371

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