Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Endolysosomal System and Proteostasis: From Development to Degeneration

31 Oct 2018

Abstract excerpt

How do neurons adapt their endolysosomal system to address the particular challenge of membrane transport across their elaborate cellular landscape and to maintain proteostasis for the lifetime of the organism? Here we review recent findings that address this central question. We discuss the cellular and molecular mechanisms of endolysosomal trafficking and the autophagy pathway in neurons, as well as their role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Calcium signaling and nucleotide metabolism
Share to Cellular transport and secretion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30381428
DOI: 10.1523/jneurosci.1665-18.2018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Endolysosomal System and Proteostasis: From Development to DegenerationPMID 30381428Read ↗

Endocytic membrane trafficking and neurodegenerative diseaseSemantic proximity Read ↗

Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseasesSemantic proximity Read ↗

Endo-lysosomal dysfunction in neurodegenerative diseases: opinion on current progress and future direction in the use of exosomes as biomarkersSemantic proximity Read ↗

Endo-IP and Lyso-IP Toolkit for Endolysosomal Profiling of Human Induced NeuronsSemantic proximity Read ↗

Neurodegenerative lysosomal disorders: A continuum from development to late ageSemantic proximity Read ↗

Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and deathSemantic proximity Read ↗

Autophagosome Biogenesis in Primary Neurons Follows an Ordered and Spatially Regulated PathwaySemantic proximity Read ↗

The endolysosomal pathway and ALS/FTD.Semantic proximity Read ↗

ER ‐phagy in neurodegenerationSemantic proximity Read ↗

Lysosomal Storage Diseases-Regulating NeurodegenerationSemantic proximity Read ↗

Towards a better understanding of the neuro-developmental role of autophagy in sickness and in healthSemantic proximity Read ↗

Role of the endolysosomal system in Parkinson’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.