Article

Direct reprogramming of human somatic cells into neuron-like cells involves a transition through a transient intermediate state

2026-05-18

Abstract excerpt

<h4>Background</h4> Direct conversion of human somatic cells into functional neurons could offer a faster way to generate patient-specific neurons for use in regenerative medicine, disease modelling, and drug development. Although it has been reported that neuronal direct reprogramming bypasses the intermediate pluripotent state, no reports have included time-lapse experiments, potentially overlooking transient i...

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Literature Corpus work: dc438184-b14e-5414-8695-7dd5de7fd4cb
DOI: 10.64898/2026.05.14.725118

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