Article

Long-lasting structural and functional maturation in transplanted human neurons reprogrammed from glial progenitor cells

2025-12-05

Abstract excerpt

Direct reprogramming of brain-resident glial progenitor cells (GPCs) into induced neurons (iN) shows great promise for future regenerative therapies for brain diseases. This type of cell conversion is facilitated by introducing lineage-specific transcription factors or small molecules to somatic cells, and can even be achieve in vivo , targeting resident glia cells in the brain for in vivo conversion. While this...

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Literature Corpus work: 27ad6884-5905-56a1-a4fd-91ad5e952fbc
DOI: 10.64898/2025.12.02.691915

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