Article

Generation of phenotypically stable and functionally mature human bone marrow MSCs derived Schwann cells via the induction of human iPSCs-derived sensory neurons

2024-09-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Phenotypically unstable Schwann cell-like cells (SCLCs), derived from mesenchymal stem cells (MSCs) require intercellular contact-mediated cues for Schwann cell (SCs)-fate commitment. Although rat dorsal root ganglion (DRG) neurons provide contact-mediated signals for the conversion of SCLCs into fate-committed SCs, the use of animal cells is clinically unaccepta...

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Literature Corpus work: 24af1da1-1d87-53e4-b357-a22faca0f2ec
DOI: 10.21203/rs.3.rs-4644070/v1

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