Article
The hedgehog signaling pathway is expressed in the adult mouse hypothalamus and modulated by fasting
2021-06-10
Abstract excerpt
The importance of the primary cilium was initially highlighted by the class of human genetic disorders known as ciliopathies. Patients with ciliopathies such as Bardet-Biedl and Alström syndrome exhibit hyperphagia-associated obesity as a core clinical phenotype. How primary cilia contribute to energy homeostasis and feeding behavior is complex and unclear, but cilia appear important in both developmental and home...
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Identifiers and source
- Literature Corpus work
- a2d63a72-416a-54ff-a635-679d9c3c2e6a
- DOI
- 10.1101/2021.06.09.447747