Article

A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification

2024-08-20

Abstract excerpt

<title>Abstract</title> Studying developmental processes in the context of the human central nervous system is essential to understand neurodevelopmental diseases. In this paper we perform a comparative functional study of the ciliopathy gene RPGRIP1L in human and mouse spinal development using in vitro 3D differentiation of pluripotent stem cells. RPGRIP1L, a causal gene of severe neurodevelopmental ciliopath...

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Literature Corpus work: 78780e82-ad37-577d-9179-3b349fdde4e2
DOI: 10.21203/rs.3.rs-4750784/v1

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