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Real-time near-infrared imaging distinguishes nasopharyngeal colonization from aspiration of <i>Streptococcus pneumoniae</i> and identifies aspiration as a trigger of severe disease

2026-08-26

Abstract excerpt

Streptococcus pneumoniae asymptomatically colonizes the nasopharynx but can invade the lower respiratory tract to cause life-threatening disease, particularly in older adults. However, whether the initial site of bacterial deposition following intranasal inoculation determines disease progression has not been directly examined. Here, we developed a near-infrared (NIR) fluorescence imaging approach using indocyanin...

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Literature Corpus work
dbc68914-1d68-5664-83ed-8c0f82407060
DOI
10.64898/2026.08.21.746383
Open publication

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Real-time near-infrared imaging distinguishes nasopharyngeal colonization from aspiration of <i>Streptococcus pneumoniae</i> and identifies aspiration as a trigger of severe diseaseDOI 10.64898/2026.08.21.746383
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