Article

The nose is the best niche for detection of pneumococcal colonisation following experimental challenge in adults of all ages

2021-05-19

Abstract excerpt

<h4>Background: </h4> Previous studies have suggested that the pneumococcal niche changes from the nose to the oropharynx with age. We use an Experimental Human Pneumococcal Challenge model to investigate pneumococcal colonisation in each anatomical niche with age. Methods Healthy adults (n = 112) were intranasally inoculated with Streptococcus pneumoniae serotype 6B (Spn6B) and were categorised as young 18-55yrs...

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Literature Corpus work: 8fa35ed7-a8b8-51b9-a453-538365d526a6
DOI: 10.21203/rs.3.rs-513376/v1

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