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Epithelial micro-invasion by <i>Streptococcus pneumoniae</i> induces epithelial-derived innate immunity during colonisation at the human mucosal surface

2018-03-13

Abstract excerpt

<h4>ABSTRACT</h4> Control of Streptococcus pneumoniae colonisation at human mucosal surfaces is critical to reducing the burden of pneumonia and invasive pneumococcal disease, interrupting transmission, and achieving herd protection. Using an Experimental Human Pneumococcal Carriage Model (EHPC), we show that S. pneumoniae colonisation is associated with epithelial surface adherence, micro-colony formation and...

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Literature Corpus work
db6a4834-e26f-5994-87da-caf98fe5afc9
DOI
10.1101/281576
Open publication

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