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In Vivo Dual RNA-Seq Analysis Reveals the Basis for Differential Tissue Tropism of Clinical Isolates of Streptococcus pneumoniae

2019-12-03

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<h4>ABSTRACT</h4> Streptococcus pneumoniae is a genetically diverse human-adapted pathogen commonly carried asymptomatically in the nasopharynx. We have recently shown that a single nucleotide polymorphism (SNP) in the raffinose pathway regulatory gene rafR accounts for a significant difference in the capacity of clonally-related strains to cause localised versus systemic infection. Here we have used dual RNA-se...

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Literature Corpus work: 352b7545-8355-56ef-b04f-da07267def79
DOI: 10.1101/862755

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<i>In Vivo</i> Dual RNA-Seq Analysis Reveals the Basis for Differential Tissue Tropism of Clinical Isolates of <i>Streptococcus pneumoniae</i>

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