Article

Commensal to pathogen switch in <i>Streptococcus pneumoniae</i> is governed by a thermosensing master regulator

2025-05-23

Abstract excerpt

Opportunistic pathogens switch from a commensal to pathogenic state by sensing and responding to a variety of environmental cues, including temperature fluctuations. Minor temperature oscillations can alert the pathogen to a changing niche ecosystem, necessitating efficient sensing and rapid integration to trigger behavioral change. This is typically achieved through master regulators, which act as umbrella system...

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Literature Corpus work: 1eaa37d7-398f-5294-8ad3-a4b17b1ac78a
DOI: 10.1101/2025.05.23.655729

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