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Article

Levetiracetam Modulates Brain Metabolic Networks and Transcriptomic Signatures in the 5XFAD Mouse Model of Alzheimer’s disease

2023-11-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>INTRODUCTION</h4> Subcritical epileptiform activity is associated with impaired cognitive function and is commonly seen in patients with Alzheimer’s disease (AD). The anti-convulsant, levetiracetam (LEV), is currently being evaluated in clinical trials for its ability to reduce epileptiform activity and improve cognitive function in AD. The purpose of the current study was to apply pharmaco...

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Literature Corpus work
db74b0c3-6bc3-55c2-89c8-c14fe632f3e2
DOI
10.1101/2023.11.10.566574
Open publication

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