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Article

Capturing needles in haystacks: a comparison of B-cell receptor sequencing methods.

BMC immunology - 5 Aug 2014

Bashford-Rogers Rachael J M, Palser Anne L, Idris Saad F, Carter Lisa, Epstein Michael, Callard Robin E, Douek Daniel C, Vassiliou George S, Follows George A, Hubank Mike, Kellam Paul

Abstract excerpt

BACKGROUND: Deep-sequencing methods are rapidly developing in the field of B-cell receptor (BCR) and T-cell receptor (TCR) diversity. These promise to revolutionise our understanding of adaptive immune dynamics, identify novel antibodies, and allow monitoring of minimal residual disease. However, different methods for BCR and TCR enrichment and amplification have been proposed. Here we perform the first...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25189176
DOI: 10.1186/s12865-014-0029-0
PMCID: PMC4243823

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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