Article

A 3D microtumour system that faithfully represents ovarian cancer minimal residual disease

2023-07-16

Abstract excerpt

<h4>Background</h4> Bulk cancer and minimal residual disease (MRD) are characterised by different molecular drivers and therefore necessitate different therapeutic strategies. However, there are currently no 3D models that can faithfully recapitulate MRD ex vivo for therapy development. <h4>Methods</h4> A microfluidic technique was implemented to construct 3D microtumours, in which tumour cells, either by them...

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Literature Corpus work: 21b66787-a6c3-5736-ba45-f34558aa1ff1
DOI: 10.1101/2023.07.15.549155

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