Article

Discriminative histone imputation using chromatin accessibility

2024-01-15

Abstract excerpt

Histone modifications (HMs) play a pivot role in various biological processes, including transcription, replication and DNA repair, significantly impacting chromatin structure. These modifications underpin the molecular mechanisms of cell-specific gene expression and complex diseases. However, annotating HMs across different cell types solely using experimental approaches is impractical due to cost and time constr...

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Literature Corpus work: db1278d6-f6c9-5e35-8ab2-2ba2745e9140
DOI: 10.1101/2024.01.11.575175

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