Article

Basset: Learning the regulatory code of the accessible genome with deep convolutional neural networks

2015-10-05

Abstract excerpt

The complex language of eukaryotic gene expression remains incompletely understood. Despite the importance suggested by many noncoding variants statistically associated with human disease, nearly all such variants have unknown mechanism. Here, we address this challenge using an approach based on a recent machine learning advance—deep convolutional neural networks (CNNs). We introduce an open source package Basset...

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Literature Corpus work: 72c2b3db-dc53-5949-8deb-4d7e468003f6
DOI: 10.1101/028399

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