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Profiling microglia from AD donors and non-demented elderly in acute human post-mortem cortical tissue

2020-03-19

Abstract excerpt

Microglia are the tissue-resident macrophages of the central nervous system (CNS). Recent studies based on bulk and single-cell RNA sequencing in mice indicate high relevance of microglia with respect to risk genes and neuro-inflammation in Alzheimer’s disease. Here, we investigated microglia transcriptomes at bulk and single cell level in non-demented elderly and AD donors using acute human post-mortem cortical b...

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Identifiers and source

Literature Corpus work
646379d7-e6da-5c94-9c0b-232c60ef6112
DOI
10.1101/2020.03.18.995332
Open publication

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Profiling microglia from AD donors and non-demented elderly in acute human post-mortem cortical tissueDOI 10.1101/2020.03.18.995332
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