Article

Activin A-activated ALK4 induces pathogenic Th17 involvement in endothelial–mesenchymal transition in systemic lupus erythematosus-associated pulmonary arterial hypertension

2025-01-25

Abstract excerpt

<h4>Objective</h4> Autoimmune diseases, such as systemic lupus erythematosus (SLE), are associated with pulmonary arterial hypertension (PAH), a condition that can lead to heart failure. However, whether T cells also contribute to the occurrence of PAH in SLE, has not been clarified. The objective of this study was to elucidate the role of Activin A signaling in the effector cells mainly involved in SLE-PAH. <h4>...

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Literature Corpus work: dae887df-6047-5a0c-b1d7-a4de5c04586e
DOI: 10.1101/2025.01.23.25321014

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