Article
Identification of ACKR4 as an immune checkpoint in pulmonary arterial hypertension
28 Jun 2023
Abstract excerpt
Objective Inflammation is recognized as a contributor in the development of pulmonary arterial hypertension (PAH), and the recruitment and functional capacity of immune cells are well-orchestrated by chemokines and their receptors. This study is aimed at identification of critical chemokines in the progression of PAH via transcriptomic analysis. Methods Differentially expressed genes (DEGs) from lungs of PAH...
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