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Article

Immunometabolic remodeling of perivascular adipose tissue in murine lupus: implications for lupus vasculopathy

2026-05-19

Abstract excerpt

<h4>Background</h4> Patients with systemic lupus erythematosus (SLE) face markedly increased cardiovascular disease (CVD) risk driven by mechanisms beyond traditional risk factors. Thoracic aortic perivascular adipose tissue (tPVAT) is dysfunctional in lupus and exacerbates endothelial dysfunction, yet the molecular basis of this dysfunction remains poorly defined. <h4>Methods</h4> Integrated multi-omics profili...

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Literature Corpus work
c7e0a651-d6f4-5ccf-86ce-89a7a514b50e
DOI
10.64898/2026.05.18.726104
Open publication

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Immunometabolic remodeling of perivascular adipose tissue in murine lupus: implications for lupus vasculopathyDOI 10.64898/2026.05.18.726104
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