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Th1-related transcription factors and cytokines in systemic lupus erythematosus

18 Dec 2023

Abstract excerpt

Systemic lupus erythematosus (SLE) is an inflammatory disorder related to immunity dysfunction. The Th1 cell family including Th1 cells, transcription factor T-bet, and related cytokines IFNγ, TNFα, IL-2, IL-18, TGF-β, and IL-12 have been widely discussed in autoimmunity, such as SLE. In this review, we will comprehensively discuss the expression profile of the Th1 cell family in both SLE patients and animal...

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PMID: 38164134
DOI: 10.3389/fimmu.2023.1305590

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