Article

LncRNA H19 facilitates polarization of M1 phenotype macrophages via miR-145-5p/PAI-1 axis in mediating systemic lupus erythematosus

2022-10-10

Abstract excerpt

LncRNAs take extensive effects in immune cells to mediate various autoimmune diseases. However, its potential role in development of SLE remains uncertain. We screened out candidate lncRNA in exosomes from SLE patients and the healthy, and was further validated in mouse model by histological examinations in vivo. Additional morphological verification was exploited to validate its biological functions by constructi...

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Literature Corpus work: d11bc225-f01b-535c-b576-14d444dab5b2
DOI: 10.21203/rs.3.rs-2125133/v1

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