Article

Quantitative <i>in vivo</i> bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts

2020-05-16

Abstract excerpt

Despite extensive research, little progress has been made in glioblastoma therapy, owing in part to a lack of adequate preclinical in vivo models to study this disease. To mitigate this, primary patient-derived cell lines, which maintain their specific stem-like phenotypes, have replaced established glioblastoma cell lines. However, due to heterogenous tumour growth inherent in glioblastoma, the use of primary ce...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dae47021-4c43-5008-9a93-10a94545b936
DOI: 10.1101/2020.05.15.098640

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Quantitative <i>in vivo</i> bioluminescence imaging of orthotopic patient-derived glioblastoma xenograftsDOI 10.1101/2020.05.15.098640Read

Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicineSemantic proximity Read

A syngeneic spontaneous zebrafish model of <i>tp53</i> -deficient, EGFR <sup>vIII</sup> , and PI3KCA <sup>H1047R</sup> -driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse <i>in vivo</i>Semantic proximity Read

High Resolution Tomographic Analysis of <i>in vitro</i> 3D Glioblastoma Tumor Model under Long-Term Drug TreatmentSemantic proximity Read

Akaluc bioluminescence offers superior sensitivity to track in vivo glioma expansionSemantic proximity Read

Generation of Glioblastoma Patient-Derived Intracranial Xenografts for Preclinical StudiesSemantic proximity Read

Modelling Glioma Stem Cell-mediated Tumorigenesis Using Zebrafish PDX SystemsSemantic proximity Read

Xenotransplantation of Human glioblastoma in Zebrafish larvae: in vivo imaging and proliferation assessmentSemantic proximity Read

Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenograftsSemantic proximity Read

Dual Lentiviral Transduction To Generate Mutant Neural Stem Cells For Glioma Research.Semantic proximity Read

Establishment, Maintenance, and In Vitro and In Vivo Applications of Primary Human Glioblastoma Multiforme (GBM) Xenograft Models for Translational Biology Studies and Drug DiscoverySemantic proximity Read

Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genesSemantic proximity Read

Positron Emission Tomography Reporter Genes and Reporter Probes: Gene and Cell Therapy ApplicationsSemantic proximity Read