Akaluc bioluminescence offers superior sensitivity to track in vivo glioma expansion

Abstract excerpt

BACKGROUND: Longitudinal tracking of tumor growth using noninvasive bioluminescence imaging (BLI) is a key approach for studies of in vivo cancer models, with particular relevance for investigations of malignant gliomas in rodent intracranial transplant paradigms. Akaluciferase (Akaluc) is a new BLI system with higher signal strength than standard firefly luciferase (Fluc). Here, we establish Akaluc BLI as a...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to bioluminescence and chemiluminescence research
• Share to Cancer Research and Treatments
• Share to Glioma Diagnosis and Treatment