Xenotransplantation of Human glioblastoma in Zebrafish larvae: in vivo imaging and proliferation assessment

Abstract excerpt

ABSTRACT Glioblastoma (GBM) is the most prevalent type of primary brain tumor. Treatment options include maximal surgical resection and drug-radiotherapy combination. However, patient prognosis remains very poor, prompting the search for new models for drug discovery and testing, especially those that allow assessment of in vivo responses to treatment. Zebrafish xenograft models have an enormous potential to...

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