Article

Modelling Glioma Stem Cell-mediated Tumorigenesis Using Zebrafish PDX Systems

2024-03-11

Abstract excerpt

<h4>Summary</h4> Glioblastoma is an aggressive brain tumour associated with high post-therapy recurrence and very poor survival rates. One of the factors contributing to the aggressive nature of this disease is the level of heterogeneity seen at the phenotypic and genetic level. Glioma Stem Cells (GSCs) are stem-like cells within the tumour with the ability to self-renew and give rise to different types of cells...

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Literature Corpus work: 97d2629e-8b90-5c73-bd39-bad1258a9977
DOI: 10.1101/2024.02.27.580776

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