Article

Large-scale identification of RBP-RNA interactions by RAPseq refines essentials of post-transcriptional gene regulation

2021-11-09

Abstract excerpt

<h4>SUMMARY</h4> Over the past decade, thousands of putative human RNA binding proteins (RBPs) have been identified and increased the demand for specifying RNA binding capacities. Here, we developed RNA affinity purification followed by sequencing (RAPseq) that enables in vitro large-scale profiling of RBP binding to native RNAs. First, by employing RAPseq, we found that vertebrate HURs recognize a conserved RNA...

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Literature Corpus work: 9c64b486-2619-5237-8ed8-d7de08e90fa5
DOI: 10.1101/2021.11.08.467743

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