Article

ROQUIN-1 binding to the transcriptome of T cells reveals conserved targets in the control of lymphopoiesis

2025-07-15

Abstract excerpt

<title>Abstract</title> <p>Defining the RNA targets of ROQUIN-1 is essential for understanding post-transcriptional gene regulation in immunity, autoimmunity, and cancer immunotherapy. We systematically mapped transcriptome-wide ROQUIN-1/RNA interactions in mouse and human lymphocytes. Novel targets were enriched in signaling molecules, transcription factors, epigenetic regulators, and mediators of immune cell di...

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Literature Corpus work: c2bb95a6-335e-58af-b9c5-c73272d441ac
DOI: 10.21203/rs.3.rs-6931797/v1

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