Article

Mapping the dynamic RNA binding proteome in human effector T cells identifies differentiation and cytotoxicity regulators

2025-12-09

Abstract excerpt

RNA-binding proteins (RBPs) are key regulators of T cell function by controlling (m)RNA fate and fine-tuning protein expression dynamics. Dysregulated RBPs can drive immune diseases and malignancies, highlighting their potential as therapeutic targets. To achieve this, a systematic analysis of the dynamic RBP–RNA interactions is required. Here, we mapped the RNA-binding proteome in human T cells and measured its a...

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Literature Corpus work: d4577c9f-7198-5713-9ab6-1283153faad7
DOI: 10.64898/2025.12.05.692493

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