Article

High concordance between hippocampal transcriptome of the intraamygdala kainic acid model and human temporal lobe epilepsy

2020-05-14

Abstract excerpt

<h4>Objective</h4> Pharmacoresistance and the lack of disease-modifying actions of current anti-seizure drugs persist as major challenges in the treatment of epilepsy. Experimental models of chemoconvulsant-induced status epilepticus remain the models of choice to discover potential anti-epileptogenic drugs but doubts remain as to the extent to which they model human pathophysiology. The aim of the present study...

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Literature Corpus work: dac00a0b-ba7c-5a0a-a7ad-39c06e44dc81
DOI: 10.1101/2020.05.12.092338

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