Article

Expression Pattern of Epilepsy Associated Genes as a Common Pathological Signature in PTE and SE models and possible therapeutics via an in-silico approach

2026-04-27

Abstract excerpt

The transition from an initial brain insult to chronic epilepsy remains a critical challenge in clinical neuroscience, often involving complex molecular shifts that are difficult to capture through single-gene analysis. This study investigated the existence of a convergent pathway of genomic instability across two distinct etiological models: iron-induced (FeCl 3 ) post-traumatic epilepsy (PTE) and lithium-piloca...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 81acef18-5fc2-5da9-bcfa-85058fcb4baf
DOI: 10.64898/2026.04.23.720518

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Expression Pattern of Epilepsy Associated Genes as a Common Pathological Signature in PTE and SE models and possible therapeutics via an in-silico approachDOI 10.64898/2026.04.23.720518Read

Identification of gene regulatory networks affected across drug-resistant epilepsiesSemantic proximity Read

Insight on the hub gene associated signatures and potential therapeutic agents in epilepsy and gliomaSemantic proximity Read

Whole transcriptome analysis of the hippocampus: toward a molecular portrait of epileptogenesisSemantic proximity Read

Identification of novel causative genes of childhood epileptic encephalopathiesSemantic proximity Read

A systems level, functional genomics analysis of chronic epilepsy.Semantic proximity Read

Epileptic Encephalopathies as Neurodegenerative Disorders.Semantic proximity Read

Single-Nucleus Transcriptomics Reveals Cell Type-Specific Remodeling and Epilepsy-Associated MicrogliaSemantic proximity Read

Personalized translational epilepsy research - Novel approaches and future perspectives: Part I: Clinical and network analysis approaches.Semantic proximity Read

Proteomic Profiling of the Hippocampus of Rats Subjected to the Pilocarpine Model of EpilepsySemantic proximity Read

High concordance between hippocampal transcriptome of the intraamygdala kainic acid model and human temporal lobe epilepsySemantic proximity Read

Integrative analysis of epilepsy-associated genes reveals expression-phenotype correlations.Semantic proximity Read