Article

Proteomic Profiling of the Hippocampus of Rats Subjected to the Pilocarpine Model of Epilepsy

2026-01-05

Abstract excerpt

<h4>Background: </h4> /Objectives: High doses of pilocarpine to rats induce status epilepticus (SE) and reproduce the main characteristics of mesial temporal epilepsy. This model is considered highly isomorphic with the human disease, reason why it has been applied to elucidate the process of epileptogenesis. <h4>Methods:</h4> Two-dimensional electrophoresis (2-DE) was employed to study the hippocampal differentia...

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Literature Corpus work: d436a834-ae8c-5cbf-b701-e61c1045c34c
DOI: 10.20944/preprints202601.0164.v1

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